SCHEMBL102381

SCHEMBL102381

CCCCCCCCCCCCCCOCC(COS(C)(=O)=O)OCCCCCCCCCCCCCC

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ LPAR1 Q92633 4/20 0.56
▸ LPAR3 Q9UBY5 4/20 0.56
▸ LPAR2 Q9HBW0 1/20 0.53
▸ TLR2 O60603 4/20 0.46
▸ DNM1 Q05193 1/20 0.44
▸ PLA2G2C Q5R387 1/20 0.43
▸ USP2 O75604 1/20 0.42
▸ CA1 P00915 8/20 0.42
▸ CA2 P00918 8/20 0.42
▸ CA9 Q16790 7/20 0.42
▸ CA12 O43570 3/20 0.42
▸ CA7 P43166 3/20 0.42
▸ CA14 Q9ULX7 3/20 0.42
▸ CA3 P07451 2/20 0.42
▸ CA4 P22748 2/20 0.42
▸ CA6 P23280 2/20 0.42
▸ CA5A P35218 2/20 0.42
▸ CA5B Q9Y2D0 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11299536 1.00 LPAR1 (0.56) LPAR1LPAR3LPAR2TLR2DNM1
SCHEMBL11299539 1.00 LPAR1 (0.56) LPAR1LPAR3LPAR2TLR2DNM1
SCHEMBL16475728 1.00 LPAR1 (0.56) LPAR1LPAR3LPAR2TLR2DNM1
SCHEMBL11299532 1.00 LPAR1 (0.56) LPAR1LPAR3LPAR2TLR2DNM1
SCHEMBL17184093 1.00 LPAR1 (0.56) LPAR1LPAR3LPAR2TLR2DNM1
SCHEMBL8912777 0.92 LPAR1 (0.48) LPAR1LPAR3LPAR2PLA2G2CUSP2
SCHEMBL26366389 0.91 LPAR1 (0.49) LPAR1LPAR3LPAR2
SCHEMBL1077368 0.88 ALDH1A1 (0.55) LPAR1LPAR3
SCHEMBL10550605 0.87 PRKD3 (0.55) LPAR1LPAR3LPAR2PLA2G2CUSP2
SCHEMBL9716262 0.87 PRKD3 (0.55) LPAR1LPAR3LPAR2PLA2G2CUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025056466-A1 POLYVINYLPYRROLIDONE STABILIZING AGENTS, COMPOSITIONS, USES, AND MANUFACTURING METHODS THEREOF GLOBAL LIFE SCIENCES SOLUTIONS CANADA ULC (CA) 2025-03-20 — — WO disclosed
EP-2567693-B1 Lipid encapsulated interfering RNA PROTIVA BIOTHERAPEUTICS INC (CA) 2015-10-21 — — EP disclosed
EP-2567693-B1 Lipid encapsulated interfering RNA PROTIVA BIOTHERAPEUTICS INC (CA) 2015-10-21 — — EP disclosed
US-8936942-B2 Polyethyleneglycol-modified lipid compounds and uses thereof PROTIVA BIOTHERAPEUTICS, INC. (CA) 2015-01-20 — — US disclosed
US-8936942-B2 Polyethyleneglycol-modified lipid compounds and uses thereof PROTIVA BIOTHERAPEUTICS, INC. (CA) 2015-01-20 — — US disclosed
US-8936942-B2 Polyethyleneglycol-modified lipid compounds and uses thereof PROTIVA BIOTHERAPEUTICS, INC. (CA) 2015-01-20 — — US disclosed
EP-1648519-B1 LIPID ENCAPSULATED INTERFERING RNA PROTIVA BIOTHERAPEUTICS INC (CA) 2014-10-08 — — EP disclosed
EP-1648519-B1 LIPID ENCAPSULATED INTERFERING RNA PROTIVA BIOTHERAPEUTICS INC (CA) 2014-10-08 — — EP disclosed
EP-2567693-A1 Lipid encapsulated interfering RNA Protiva Biotherapeutics Inc. (CA) 2013-03-13 — — EP disclosed
EP-1664316-B1 POLYETHYLENEGLYCOL-MODIFIED LIPID COMPOUNDS AND USES THEREOF PROTIVA BIOTHERAPEUTICS INC (CA) 2012-08-29 — — EP disclosed
US-7803397-B2 Polyethyleneglycol-modified lipid compounds and uses thereof PROTIVA BIOTHERAPEUTICS, INC. (CA) 2010-09-28 — — US disclosed
US-7803397-B2 Polyethyleneglycol-modified lipid compounds and uses thereof PROTIVA BIOTHERAPEUTICS, INC. (CA) 2010-09-28 — — US disclosed
US-20060240093-A1 LIPID ENCAPSULATED INTERFERING RNA PROTIVA BIOTHERAPEUTICS, INC. (CA) 2006-10-26 — — US disclosed
WO-2006074546-A1 LIPID ENCAPSULATED INTERFERING RNA PROTIVA BIOTHERAPEUTICS, INC. (CA) 2006-07-20 — — WO disclosed
EP-1664316-A1 POLYETHYLENEGLYCOL-MODIFIED LIPID COMPOUNDS AND USES THEREOF Protiva Biotherapeutics Inc. (CA) 2006-06-07 — — EP disclosed
EP-1648519-A2 LIPID ENCAPSULATED INTERFERING RNA Protiva Biotherapeutics Inc. (CA) 2006-04-26 — — EP disclosed
US-20050175682-A1 Polyethyleneglycol-modified lipid compounds and uses thereof PROTIVA BIOTHERAPEUTICS, INC. (CA) 2005-08-11 — — US disclosed
US-20050064595-A1 Lipid encapsulated interfering RNA PROTIVA BIOTHERAPEUTICS, INC. (CA) 2005-03-24 — — US disclosed
WO-2005026372-A1 POLYETHYLENEGLYCOL-MODIFIED LIPID COMPOUNDS AND USES THEREOF PROTIVA BIOTHERAPEUTICS, INC. (CA) 2005-03-24 — — WO disclosed
WO-2005007196-A2 LIPID ENCAPSULATED INTERFERING RNA PROTIVA BIOTHERAPEUTICS, INC. (CA) 2005-01-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050064595-A1 Lipid encapsulated interfering RNA ABHD16A, LDLR, RNASE1 LPAR1 59/4885LPAR3 40/4885LPAR2 71/4885
US-20050175682-A1 Polyethyleneglycol-modified lipid compounds and uses thereof LIPA, PNLIP, PLTP LPAR1 65/4885LPAR3 88/4885LPAR2 69/4885
US-20060240093-A1 LIPID ENCAPSULATED INTERFERING RNA ABHD16A, LDLR, RNASE1 LPAR1 59/4885LPAR3 40/4885LPAR2 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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