Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 18/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11572618 | 1.00 | TBXAS1 (0.63) | TBXAS1ALDH1A1ABL1RIN1 | |
| SCHEMBL14499226 | 0.98 | TBXAS1 (0.60) | TBXAS1ALDH1A1ABL1RIN1 | |
| SCHEMBL941695 | 0.94 | TBXAS1 (0.56) | TBXAS1ALDH1A1ABL1RIN1 | |
| SCHEMBL9786222 | 0.89 | TBXAS1 (0.69) | TBXAS1ALDH1A1 | |
| SCHEMBL47374 | 0.88 | TBXAS1 (0.59) | TBXAS1ALDH1A1ABL1RIN1 | |
| SCHEMBL7824835 | 0.87 | TBXAS1 (0.55) | TBXAS1ALDH1A1ABL1RIN1 | |
| SCHEMBL29729354 | 0.86 | TBXAS1 (0.63) | TBXAS1 | |
| SCHEMBL7444582 | 0.85 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL11223282 | 0.85 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL11221333 | 0.85 | TBXAS1 (0.67) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54109973-A | — | — | None | — | — | JP | disclosed |
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| US-5081245-A | Selective antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0378763-A1 | Lipids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |
| EP-0356765-A2 | Carboxylic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4355170-A | ANTIINFLAMMATORY, HYPERTENSIVE, ANTIASTHMATIC AGENTS, A THROMBOXANE SYNTHETASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| US-4256757-A | ANTIINFLAMMATORY AND HYPOTENSIVE AGENTS; THROMBOSIS; ASTHMA; NERVOUS SYSTEM DISORDERS | ONO PHARMACEUTICAL CO., LTD. | 1981-03-17 | — | — | US | disclosed |
| JP-S54109973-A | NOVEL IMIDAZOLE DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1979-08-29 | — | — | JP | disclosed |