Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.46 |
| ▸ | GNPAT | O15228 | 2/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716590 | 1.00 | FOLH1 (0.51) | FOLH1CPB2GNPATSLC6A5NOD1 | |
| SCHEMBL9716599 | 1.00 | FOLH1 (0.51) | FOLH1CPB2GNPATSLC6A5NOD1 | |
| SCHEMBL9716627 | 0.95 | FOLH1 (0.58) | FOLH1CPB2GNPATSLC6A5SLC15A2 | |
| SCHEMBL9716630 | 0.95 | FOLH1 (0.58) | FOLH1CPB2GNPATSLC6A5SLC15A2 | |
| SCHEMBL27793445 | 0.87 | NOD1 (0.56) | FOLH1CPB2GNPATSLC6A5NOD1 | |
| SCHEMBL29674589 | 0.87 | NOD1 (0.56) | FOLH1CPB2GNPATSLC6A5NOD1 | |
| SCHEMBL4078081 | 0.87 | FOLH1 (0.50) | FOLH1CPB2GNPATSLC6A5NOD1 | |
| SCHEMBL27793444 | 0.87 | NOD1 (0.56) | FOLH1CPB2GNPATSLC6A5NOD1 | |
| SCHEMBL29406243 | 0.87 | NOD1 (0.56) | FOLH1CPB2GNPATSLC6A5NOD1 | |
| SCHEMBL20332470 | 0.86 | FOLH1 (0.49) | FOLH1CPB2GNPATSLC6A5NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |