Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31390220 | 1.00 | LMNA (0.82) | LMNATDP1ALDH1A1PSMB5KMT2A | |
| SCHEMBL9716661 | 1.00 | LMNA (0.82) | LMNATDP1ALDH1A1PSMB5KMT2A | |
| SCHEMBL9234559 | 0.94 | LMNA (0.73) | LMNATDP1ALDH1A1PSMB5KMT2A | |
| SCHEMBL5612699 | 0.94 | LMNA (0.73) | LMNATDP1ALDH1A1PSMB5KMT2A | |
| SCHEMBL10665563 | 0.94 | LMNA (0.73) | LMNATDP1ALDH1A1PSMB5KMT2A | |
| SCHEMBL9232064 | 0.93 | LMNA (0.76) | LMNATDP1ALDH1A1PSMB5KMT2A | |
| SCHEMBL9232060 | 0.93 | LMNA (0.76) | LMNATDP1ALDH1A1PSMB5KMT2A | |
| SCHEMBL7778087 | 0.92 | LMNA (0.71) | LMNATDP1ALDH1A1PSMB5KMT2A | |
| SCHEMBL9716670 | 0.92 | LMNA (0.71) | LMNATDP1ALDH1A1PSMB5KMT2A | |
| SCHEMBL4889588 | 0.92 | LMNA (0.71) | LMNATDP1ALDH1A1PSMB5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | claimed |
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |