Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.62 |
| ▸ | NOD1 | Q9Y239 | 14/20 | 0.59 |
| ▸ | GNPAT | O15228 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716812 | 1.00 | SLC6A5 (0.62) | SLC6A5NOD1GNPATFOLH1ITGB3 | |
| SCHEMBL9716672 | 1.00 | SLC6A5 (0.62) | SLC6A5NOD1GNPATFOLH1ITGB3 | |
| SCHEMBL5060759 | 0.95 | SLC6A5 (0.68) | SLC6A5NOD1GNPATFOLH1ITGB3 | |
| SCHEMBL343100 | 0.95 | SLC6A5 (0.68) | SLC6A5NOD1GNPATFOLH1ITGB3 | |
| SCHEMBL9664054 | 0.90 | SLC6A5 (0.75) | SLC6A5NOD1GNPATITGB3ITGA2B | |
| SCHEMBL9664060 | 0.90 | SLC6A5 (0.75) | SLC6A5NOD1GNPATITGB3ITGA2B | |
| SCHEMBL9664051 | 0.90 | SLC6A5 (0.75) | SLC6A5NOD1GNPATITGB3ITGA2B | |
| SCHEMBL8205590 | 0.89 | SLC6A5 (0.78) | SLC6A5NOD1ITGB3ITGA2B | |
| SCHEMBL9664648 | 0.89 | SLC6A5 (0.78) | SLC6A5NOD1ITGB3ITGA2B | |
| SCHEMBL9666161 | 0.89 | SLC6A5 (0.78) | SLC6A5NOD1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |