Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.85 |
| ▸ | NOD1 | Q9Y239 | 13/20 | 0.75 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245563 | 1.00 | SLC6A5 (0.85) | SLC6A5NOD1ITGB3ITGA2BFOLH1 | |
| SCHEMBL343693 | 1.00 | SLC6A5 (0.85) | SLC6A5NOD1ITGB3ITGA2BFOLH1 | |
| SCHEMBL9716727 | 1.00 | SLC6A5 (0.85) | SLC6A5NOD1ITGB3ITGA2BFOLH1 | |
| SCHEMBL5946236 | 1.00 | SLC6A5 (0.85) | SLC6A5NOD1ITGB3ITGA2BFOLH1 | |
| SCHEMBL2166697 | 1.00 | SLC6A5 (0.85) | SLC6A5NOD1ITGB3ITGA2BFOLH1 | |
| SCHEMBL1487710 | 1.00 | SLC6A5 (0.85) | SLC6A5NOD1ITGB3ITGA2BFOLH1 | |
| SCHEMBL1982744 | 1.00 | SLC6A5 (0.85) | SLC6A5NOD1ITGB3ITGA2BFOLH1 | |
| SCHEMBL15474 | 1.00 | SLC6A5 (0.85) | SLC6A5NOD1ITGB3ITGA2BFOLH1 | |
| SCHEMBL342965 | 1.00 | SLC6A5 (0.85) | SLC6A5NOD1ITGB3ITGA2BFOLH1 | |
| SCHEMBL4020128 | 1.00 | SLC6A5 (0.85) | SLC6A5NOD1ITGB3ITGA2BFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |