Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689061 | 1.00 | PTGS1 (0.43) | PTGS1GLO1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL5071853 | 0.89 | PTGS1 (0.55) | PTGS1GLO1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL5071854 | 0.89 | PTGS1 (0.55) | PTGS1GLO1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL5873600 | 0.87 | PTGS1 (0.49) | PTGS1GLO1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL2616646 | 0.87 | PTGS1 (0.49) | PTGS1GLO1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL2616636 | 0.83 | PTGS1 (0.49) | PTGS1GLO1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8505049 | 0.83 | PTGS1 (0.68) | PTGS1GLO1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8503596 | 0.83 | PTGS1 (0.68) | PTGS1GLO1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8872407 | 0.83 | GLO1 (0.54) | GLO1ALDH1A1ALOX15HSD17B10TSHR | |
| SCHEMBL7551459 | 0.83 | GLO1 (0.54) | GLO1ALDH1A1ALOX15HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118866-A | PREPARATION OF POLYENE ALDEHYDES | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4543417-A | ω,ω-Diacyloxy-2,6-dimethyl-octatrienoates and -octatrienals, their preparation and their use for the synthesis of terpene compounds | BASF AKTIENGESELLSCHAFT (DE) | 1985-09-24 | — | — | US | disclosed |
| US-4026910-A | Oxidation process using nickel peroxide oxidizing agents | HOFFMANN-LA ROCHE INC. (US) | 1977-05-31 | — | — | US | disclosed |
| US-3989758-A | Monoacetals of unsaturated aliphatic dialdehydes | HOFFMANN-LA ROCHE INC. (US) | 1976-11-02 | — | — | US | disclosed |