Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716914 | 0.84 | ITGB3 (0.60) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9716958 | 0.84 | ITGB3 (0.60) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9716926 | 0.84 | ITGB3 (0.60) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9716946 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9716932 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9716942 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9716833 | 0.79 | ITGB3 (0.57) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9716964 | 0.78 | CNR1 (0.53) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL7075139 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 | |
| SCHEMBL9716873 | 0.75 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP1A2CYP2D6CYP2C9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992009561-A1 | NEW AMIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-06-11 | — | — | WO | disclosed |