Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392560 | 0.92 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL269 | 0.84 | AGTR1 (0.85) | AGTR1AGTR2 | |
| SCHEMBL773 | 0.83 | AGTR1 (0.78) | AGTR1AGTR2 | |
| SCHEMBL597 | 0.82 | AGTR1 (0.84) | AGTR1AGTR2 | |
| SCHEMBL628 | 0.81 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL627 | 0.81 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL226 | 0.81 | AGTR1 (1.00) | AGTR1AGTR2 | |
| SCHEMBL560 | 0.81 | AGTR1 (0.74) | AGTR1AGTR2 | |
| SCHEMBL7939321 | 0.81 | AGTR1 (0.98) | AGTR1AGTR2 | |
| SCHEMBL561 | 0.81 | AGTR1 (0.74) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013564-A1 | COMBINATION OF AN ANGIOTENSIN II ANTAGONIST OR RENIN INHIBITOR WITH A NEUTRAL ENDOPEPTIDASE INHIBITOR | SCHERING CORPORATION (US) | 1992-08-20 | — | — | WO | disclosed |
| EP-0498361-A2 | Combination of an angiotensin II antagonist or renin inhibitor with a neutral endopeptidase inhibitor | SCHERING CORPORATION (US) | 1992-08-12 | — | — | EP | disclosed |