Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 2/20 | 0.67 |
| ▸ | CA9 | Q16790 | 2/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.67 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Naphthol SCHEMBL11250007 | 0.85 | CYP1A2 (0.77) | HSD17B10ALDH1A1CYP3A4CA2LMNA | |
| SCHEMBL29351230 | 0.85 | IDO1 (0.73) | HSD17B10ALDH1A1CYP3A4CA2LMNA | |
| SCHEMBL28327 | 0.85 | IDO1 (0.73) | HSD17B10ALDH1A1CYP3A4CA2LMNA | |
| SCHEMBL4869305 | 0.85 | IDO1 (0.73) | HSD17B10ALDH1A1CYP3A4CA2LMNA | |
| Phenol SCHEMBL8526528 | 0.83 | IDO1 (0.63) | HSD17B10ALDH1A1CYP3A4CA2LMNA | |
| Resorcinol SCHEMBL1449408 | 0.82 | CA2 (0.75) | HSD17B10ALDH1A1CYP3A4CA2LMNA | |
| Hydroquinone SCHEMBL21552049 | 0.82 | IDO1 (0.61) | HSD17B10ALDH1A1CYP3A4CA2LMNA | |
| SCHEMBL18241092 | 0.82 | CYP1A2 (0.58) | HSD17B10CYP3A4IDO1TDP1TSHR | |
| Hydrochloric Acid SCHEMBL28326959 | 0.82 | IDO1 (0.69) | HSD17B10ALDH1A1CYP3A4CA2LMNA | |
| SCHEMBL28427946 | 0.82 | IDO1 (0.69) | HSD17B10ALDH1A1CYP3A4CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247580-B1 | THERMOPLASTIC COMPOSITION OF CRYSTALLINE POLYOLEFIN AND ETHYLENE-CONTAINING COPOLYMER | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-12 | — | — | EP | disclosed |
| US-4758629-A | Thermoplastic compositions of crystalline polyolefin and ethylene-containing copolymer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0247580-A2 | Thermoplastic composition of crystalline polyolefin and ethylene-containing copolymer | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-02 | — | — | EP | disclosed |