Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213067 | 0.97 | PTPN1 (0.51) | PTPN1PTPN2PTPN6TSHRBCL2 | |
| SCHEMBL11217534 | 0.97 | PTPN1 (0.51) | PTPN1PTPN2PTPN6TSHRBCL2 | |
| SCHEMBL30612910 | 0.84 | PTPN1 (0.65) | PTPN1PTPN2PTPN6TSHRKDM4E | |
| SCHEMBL10536145 | 0.84 | PTPN1 (0.56) | PTPN1PTPN2PTPN6TSHRBCL2 | |
| SCHEMBL112902 | 0.84 | PTPN1 (0.65) | PTPN1PTPN2PTPN6TSHRKDM4E | |
| Zinc Ion SCHEMBL10758632 | 0.84 | ALDH1A1 (0.45) | PTPN1PTPN2PTPN6KDM4EALDH1A1 | |
| SCHEMBL10976408 | 0.84 | KDM4E (0.50) | PTPN1PTPN2PTPN6KDM4EALDH1A1 | |
| Bicarbonate SCHEMBL21899873 | 0.83 | PTPN1 (0.63) | PTPN1PTPN2PTPN6TSHRKDM4E | |
| Bicarbonate SCHEMBL236871 | 0.83 | PTPN1 (0.63) | PTPN1PTPN2PTPN6TSHRKDM4E | |
| Zinc Ion SCHEMBL8428515 | 0.80 | KDM4E (0.40) | PTPN1PTPN2PTPN6TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329460-B1 | STABILISED MACROLIDE COMPOSITIONS | AMERICAN CYANAMID COMPANY (US) | 1992-05-20 | — | — | EP | claimed |