SCHEMBL971706

SCHEMBL971706

c1ccc(-c2cc(-c3ccccc3)cc(-c3ccc4nc(-c5ccc(-c6c7ccccc7c(-c7ccc8ccccc8c7)c7ccccc67)cc5)cn4c3)c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 15/20 0.63
ALDH1A1 P00352 5/20 0.63
ALDH1A2 O94788 1/20 0.63
SLC2A1 P11166 1/20 0.58
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TP53 P04637 1/20 0.47
PKM P14618 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
CDK5 Q00535 1/20 0.47
KMT2A Q03164 1/20 0.47
CDK5R1 Q15078 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HSD17B10 Q99714 1/20 0.47
EGLN1 Q9GZT9 1/20 0.42
CYP2C9 P11712 1/20 0.42
NR4A2 P43354 1/20 0.42
KCNH2 Q12809 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL785129 0.97 ALDH1A3 (0.67) ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1
SCHEMBL13454312 0.96 ALDH1A3 (0.65) ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1
SCHEMBL18288730 0.95 ALDH1A3 (0.67) ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1
SCHEMBL18288722 0.95 ALDH1A3 (0.67) ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1
SCHEMBL785387 0.92 ALDH1A3 (0.57) ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1
SCHEMBL972538 0.92 ALDH1A3 (0.61) ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1
SCHEMBL13454296 0.91 ALDH1A3 (0.68) ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1
SCHEMBL974085 0.89 ALDH1A3 (0.55) ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1
SCHEMBL13454269 0.88 ALDH1A3 (0.81) ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1
SCHEMBL13454287 0.88 ALDH1A3 (0.81) ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7867629-B2 Nitrogenous heterocyclic derivative and organic electroluminescent element employing the same IDEMITSU KOSAN CO., LTD. (JP) 2011-01-11 US disclosed