Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717230 | 0.96 | SLC6A2 (0.49) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9717268 | 0.89 | RARB (0.54) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9324332 | 0.85 | HSD17B3 (0.51) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9405582 | 0.85 | HSD17B3 (0.51) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9717247 | 0.85 | RARB (0.59) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9717228 | 0.85 | NPC1 (0.51) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9324302 | 0.83 | HSD17B3 (0.56) | THRATHRB | |
| SCHEMBL9717225 | 0.82 | ACE2 (0.50) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL9405697 | 0.82 | RARB (0.49) | RARBMEN1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL9405700 | 0.82 | RARB (0.49) | RARBMEN1KMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137653-A | Alkanoyl ester compounds and their intermediates and method of producing the same | NIPPON MINING CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0311692-B1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| EP-0311692-A1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1989-04-19 | — | — | EP | disclosed |