SCHEMBL9717280

SCHEMBL9717280

C=CCOC(=O)Oc1ccc(C(=O)O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
HTT P42858 2/20 0.49
CSNK2A2 P19784 1/20 0.45
CSNK2A1 P68400 1/20 0.45
HSD17B10 Q99714 2/20 0.45
KMT2A Q03164 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
PKM P14618 1/20 0.42
CYP3A4 P08684 1/20 0.42
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
RXRG P48443 1/20 0.41
POLB P06746 2/20 0.40
NPC1 O15118 1/20 0.40
MAPT P10636 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9717293 0.95 HSD17B10 (0.53) ALDH1A1L3MBTL1HTTCSNK2A2CSNK2A1
SCHEMBL10870487 0.89 CYP3A4 (0.50) ALDH1A1HSD17B10KMT2ACA1CA2
SCHEMBL6152601 0.88 ELANE (0.49) ALDH1A1HSD17B10CYP3A4POLBNPC1
SCHEMBL10349842 0.85 CYP3A4 (0.41) ALDH1A1L3MBTL1HTTHSD17B10KMT2A
SCHEMBL545547 0.84 CYP3A4 (0.55) ALDH1A1L3MBTL1HSD17B10KMT2ACA1
SCHEMBL6152948 0.84 CYP3A4 (0.46) ALDH1A1HTTHSD17B10KMT2ACA1
SCHEMBL31059003 0.84 HTT (0.54) ALDH1A1L3MBTL1HTTHSD17B10PKM
Bicarbonate SCHEMBL23748029 0.83 CYP3A4 (0.53) ALDH1A1L3MBTL1HSD17B10KMT2ACA1
Formaldehyde SCHEMBL28598678 0.83 CYP3A4 (0.53) ALDH1A1L3MBTL1HSD17B10KMT2ACA1
SCHEMBL9717273 0.83 ALDH1A1 (0.48) ALDH1A1HSD17B10CA1CA2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0311692-B1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1992-07-08 EP claimed
EP-0311692-A1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1989-04-19 EP claimed
US-5137653-A Alkanoyl ester compounds and their intermediates and method of producing the same NIPPON MINING CO., LTD. (JP) 1992-08-11 US disclosed
EP-0311692-B1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1992-07-08 EP disclosed
EP-0216530-B1 LIQUID CRYSTAL CARBONATOBENZOIC ACID DERIVATIVE AND COMPOSITION Chisso Corporation (JP) 1991-10-23 EP disclosed
EP-0311692-A1 NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION NIPPON MINING COMPANY LIMITED (JP) 1989-04-19 EP disclosed
US-4816181-A FOR DISPLAYS CHISSO CORPORATION (JP) 1989-03-28 US disclosed
EP-0216530-A1 Liquid crystal carbonatobenzoic acid derivative and composition Chisso Corporation (JP) 1987-04-01 EP disclosed