Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811862 | 0.95 | PRMT1 (0.60) | TSHRLMNAATMMEN1MAPT | |
| SCHEMBL30410272 | 0.95 | ATM (0.55) | TSHRLMNASLC22A6ATMMEN1 | |
| SCHEMBL15399971 | 0.95 | TSHR (0.65) | TSHRLMNASLC22A6ATMMEN1 | |
| SCHEMBL31317706 | 0.93 | PRMT1 (0.64) | TSHRLMNAATMMEN1MAPT | |
| SCHEMBL31317673 | 0.93 | PRMT1 (0.64) | TSHRLMNAATMMEN1MAPT | |
| SCHEMBL31317640 | 0.93 | PRMT1 (0.64) | TSHRLMNAATMMEN1MAPT | |
| SCHEMBL16620647 | 0.93 | PRMT1 (0.64) | TSHRLMNAATMMEN1MAPT | |
| SCHEMBL2806091 | 0.92 | ATM (0.57) | TSHRLMNASLC22A6ATMMEN1 | |
| SCHEMBL28757328 | 0.91 | PRMT1 (0.68) | TSHRLMNASLC22A6PRMT1EPHX2 | |
| SCHEMBL12999626 | 0.90 | ATM (0.55) | TSHRLMNASLC22A6ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011640-A1 | MEMANTINE DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 广州市恒诺康医药科技有限公司 | 2025-01-16 | — | — | WO | disclosed |
| US-5086104-A | Mixture of thermoplastic resin, elastomer and amide compound, excellent toughtness, heat resistance and durability | POLYPLASTICS CO., LTD. (JP) | 1992-02-04 | — | — | US | disclosed |