Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267491 | 0.95 | DGKA (0.62) | DGKADNM1NAAAHTR2CPRSS1 | |
| SCHEMBL8430388 | 0.95 | DGKA (0.58) | DGKADNM1NAAAHTR2CPRSS1 | |
| SCHEMBL8623593 | 0.94 | DGKA (0.61) | DGKADNM1NAAAHTR2CPRSS1 | |
| SCHEMBL7941998 | 0.92 | DGKA (0.62) | DGKADNM1NAAAHTR2CPRSS1 | |
| SCHEMBL11908905 | 0.92 | DGKA (0.62) | DGKADNM1NAAAHTR2CPRSS1 | |
| SCHEMBL11909432 | 0.92 | DGKA (0.62) | DGKADNM1NAAAHTR2CPRSS1 | |
| SCHEMBL7938480 | 0.92 | DGKA (0.62) | DGKADNM1NAAAHTR2CPRSS1 | |
| SCHEMBL9706868 | 0.92 | DGKA (0.62) | DGKADNM1NAAAHTR2CPRSS1 | |
| SCHEMBL11908231 | 0.92 | DGKA (0.62) | DGKADNM1NAAAHTR2CPRSS1 | |
| SCHEMBL5730879 | 0.92 | DGKA (0.62) | DGKADNM1NAAAHTR2CPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5127934-A | STABILIZED COMPOSITIONS COMPRISING ISOTHIAZOLONES AND EPOXIDES | ROHM AND HAAS COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0342852-B1 | ORGANIC STABILIZERS | ROHM AND HAAS COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| EP-0342852-A1 | Organic stabilizers | ROHM AND HAAS COMPANY (US) | 1989-11-23 | — | — | EP | disclosed |