SCHEMBL9717435

SCHEMBL9717435

NC(=O)c1cccc(C(=O)N(CCC(=O)O)CCC(=O)O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
PARP1 P09874 12/20 0.44
PPARG P37231 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HPGD P15428 1/20 0.41
MEP1B Q16820 1/20 0.41
PARP10 Q53GL7 4/20 0.40
PARP15 Q460N3 2/20 0.40
PARP14 Q460N5 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4581154 0.83 PARP1 (0.47) MEN1KMT2APARP1TDP1POLB
SCHEMBL2206850 0.82 TP53 (0.51) KMT2APARP1TDP1HPGD
SCHEMBL16094936 0.82 PARP1 (0.50) MEN1KMT2APARP1TDP1POLB
Acetic Acid SCHEMBL6139768 0.81 TP53 (0.47) MEN1KMT2APARP1TDP1HPGD
SCHEMBL7403701 0.81 ITGB3 (0.50)
Hydrochloric Acid SCHEMBL3355966 0.81 TP53 (0.50) KMT2APARP1TDP1HPGD
Hydrochloric Acid SCHEMBL3352609 0.81 TP53 (0.50) KMT2APARP1TDP1HPGD
SCHEMBL9340015 0.79 HPGD (0.43) MEN1KMT2APARP1TDP1POLB
Adipic Acid SCHEMBL28590163 0.79 MEN1 (0.57) MEN1KMT2APARP1TDP1POLB
Adipic Acid SCHEMBL28590164 0.79 MEN1 (0.57) MEN1KMT2APARP1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5086104-A Mixture of thermoplastic resin, elastomer and amide compound, excellent toughtness, heat resistance and durability POLYPLASTICS CO., LTD. (JP) 1992-02-04 US disclosed