Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 8/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717590 | 1.00 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1PPARAPPARGTRPA1 | |
| SCHEMBL9717589 | 1.00 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1PPARAPPARGTRPA1 | |
| SCHEMBL9717485 | 0.99 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1PPARAPPARGTRPA1 | |
| SCHEMBL9717491 | 0.99 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1PPARAPPARGTRPA1 | |
| SCHEMBL9721410 | 0.99 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1PPARAPPARGTRPA1 | |
| SCHEMBL9717519 | 0.96 | FFAR4 (0.41) | CYSLTR2CYSLTR1PPARAPPARGTRPA1 | |
| SCHEMBL9717525 | 0.96 | FFAR4 (0.41) | CYSLTR2CYSLTR1PPARAPPARGTRPA1 | |
| SCHEMBL9717532 | 0.96 | FFAR4 (0.41) | CYSLTR2CYSLTR1PPARAPPARGTRPA1 | |
| SCHEMBL9717566 | 0.93 | LMNA (0.39) | CYSLTR2CYSLTR1PPARAPPARGTRPA1 | |
| SCHEMBL9717559 | 0.93 | LMNA (0.39) | CYSLTR2CYSLTR1PPARAPPARGTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240256-B1 | COMPOUNDS USEFUL IN TREATING SICKLE CELL ANEMIA | MERCK & CO. INC. (US) | 1992-04-29 | — | — | EP | disclosed |
| US-4751244-A | NITROALKENYL CARBOXYLIC ACIDS | MERCK & CO., INC. (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0240256-A2 | Compounds useful in treating sickle cell anemia | MERCK & CO. INC. (US) | 1987-10-07 | — | — | EP | disclosed |