Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | ABL2 | P42684 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717631 | 1.00 | FBP1 (0.56) | FBP1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL9717632 | 0.84 | FBP1 (0.59) | FBP1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL10772748 | 0.82 | FBP1 (0.65) | FBP1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL9656291 | 0.80 | FBP1 (0.62) | FBP1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL9657482 | 0.80 | FBP1 (0.62) | FBP1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL28593122 | 0.78 | FBP1 (0.56) | FBP1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL28898306 | 0.78 | FBP1 (0.59) | FBP1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL10839774 | 0.76 | FBP1 (0.57) | FBP1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL10839779 | 0.76 | FBP1 (0.57) | FBP1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL9717619 | 0.76 | FBP1 (0.57) | FBP1LMNAMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240256-B1 | COMPOUNDS USEFUL IN TREATING SICKLE CELL ANEMIA | MERCK & CO. INC. (US) | 1992-04-29 | — | — | EP | disclosed |
| EP-0240256-A2 | Compounds useful in treating sickle cell anemia | MERCK & CO. INC. (US) | 1987-10-07 | — | — | EP | disclosed |