Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717754 | 1.00 | MEN1 (0.52) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL9506785 | 0.90 | PTPN11 (0.52) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL9506778 | 0.90 | PTPN11 (0.52) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL9177007 | 0.88 | MEN1 (0.60) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL8081716 | 0.88 | MEN1 (0.60) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL8851788 | 0.86 | ALDH1A1 (0.56) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL8851790 | 0.86 | ALDH1A1 (0.56) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL24213305 | 0.85 | NPC1 (0.59) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL5838349 | 0.85 | NPC1 (0.59) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL5838346 | 0.85 | NPC1 (0.59) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259530-B1 | METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES | CHEMIPRO KASEI KAISHA LTD (JP) | 1992-04-08 | — | — | EP | disclosed |