Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.66 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | CDC42 | P60953 | 1/20 | 0.66 |
| ▸ | RAC1 | P63000 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9284416 | 0.88 | TDP1 (1.00) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL8194894 | 0.85 | TDP1 (0.78) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL505811 | 0.84 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL505799 | 0.84 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL8754690 | 0.84 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL505819 | 0.84 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL29403959 | 0.84 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL9551659 | 0.84 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL29508603 | 0.84 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL15479224 | 0.84 | TDP1 (0.76) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298395-B1 | A PROCESS FOR THE OPTICAL RESOLUTION OF 2-(6-METHOXY-2-NAPHTHYL) PROPIONIC ACID | PROFARMACO NOBEL S.r.l. (IT) | 1992-01-29 | — | — | EP | claimed |
| US-4865770-A | SEEDING SUPERSATURATED SOLUTION OF ETHYLAMINE SALT | INDUSTRIA CHEMICA PROFARMACO S.P.A. (IT) | 1989-09-12 | — | — | US | claimed |
| EP-0298395-A1 | A process for the optical resolution of 2-(6-methoxy-2-naphthyl) propionic acid | PROFARMACO NOBEL S.r.l. (IT) | 1989-01-11 | — | — | EP | claimed |
| EP-0298395-B1 | A PROCESS FOR THE OPTICAL RESOLUTION OF 2-(6-METHOXY-2-NAPHTHYL) PROPIONIC ACID | PROFARMACO NOBEL S.r.l. (IT) | 1992-01-29 | — | — | EP | disclosed |
| US-4865770-A | SEEDING SUPERSATURATED SOLUTION OF ETHYLAMINE SALT | INDUSTRIA CHEMICA PROFARMACO S.P.A. (IT) | 1989-09-12 | — | — | US | disclosed |
| EP-0298395-A1 | A process for the optical resolution of 2-(6-methoxy-2-naphthyl) propionic acid | PROFARMACO NOBEL S.r.l. (IT) | 1989-01-11 | — | — | EP | disclosed |