Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932077 | 0.79 | MAPT (0.48) | MAPTLMNAL3MBTL1PTPN1ACP1 | |
| SCHEMBL592859 | 0.79 | MAPT (0.48) | MAPTLMNAL3MBTL1PTPN1ACP1 | |
| SCHEMBL16198983 | 0.79 | MAPT (0.48) | MAPTLMNAL3MBTL1PTPN1ACP1 | |
| SCHEMBL13523341 | 0.76 | PTPN1 (0.35) | MAPTLMNAPTPN1ACP1CDC25B | |
| SCHEMBL7769389 | 0.76 | MAPT (0.34) | MAPTPTPN1ACP1CDC25BRECQL | |
| SCHEMBL2794781 | 0.67 | MAPT (0.46) | MAPTLMNAL3MBTL1PTPN1ACP1 | |
| SCHEMBL9541659 | 0.67 | DUSP3 (0.42) | MAPTLMNAL3MBTL1PTPN1ACP1 | |
| SCHEMBL14306447 | 0.67 | DUSP3 (0.42) | MAPTLMNAL3MBTL1PTPN1ACP1 | |
| SCHEMBL736870 | 0.66 | — | — | |
| SCHEMBL7640225 | 0.65 | MAPT (0.33) | MAPTKDM4ETP53MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162366-A | Antioxidant composition in vivo comprising enol form δ-lactone of diketogulonic acid | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | claimed |
| EP-0439187-A2 | Antioxidant composition in vivo comprising enol form delta-lactone of diketogulonic acid | Kimoto, Eiji (JP) | 1991-07-31 | — | — | EP | claimed |
| JP-3251529-A | — | — | None | — | — | JP | disclosed |
| JP-2200684-A | — | — | None | — | — | JP | disclosed |
| US-5162366-A | Antioxidant composition in vivo comprising enol form δ-lactone of diketogulonic acid | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| US-5162366-A | Antioxidant composition in vivo comprising enol form δ-lactone of diketogulonic acid | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| JP-H03251529-A | MEDICINE FOR IN VIVO ANTIOXIDATION CONTAINING ENOL TYPE DELTA-LACTONE OF DIKETOGULONIC ACID | KIMOTO EIJI | 1991-11-11 | — | — | JP | disclosed |
| EP-0439187-A2 | Antioxidant composition in vivo comprising enol form delta-lactone of diketogulonic acid | Kimoto, Eiji (JP) | 1991-07-31 | — | — | EP | disclosed |
| EP-0439187-A2 | Antioxidant composition in vivo comprising enol form delta-lactone of diketogulonic acid | Kimoto, Eiji (JP) | 1991-07-31 | — | — | EP | disclosed |
| JP-H02200684-A | ENOL-TYPE DELTA-LACTONE OF DIKETOGULONIC ACID AND PRODUCTION THEREOF | KIMOTO EIJI | 1990-08-08 | — | — | JP | disclosed |