Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15681491 | 0.83 | MAPT (0.34) | MAPTKDM4ETP53MAPK1CYP2C19 | |
| SCHEMBL15681492 | 0.83 | MAPT (0.34) | MAPTKDM4ETP53MAPK1CYP2C19 | |
| SCHEMBL112481 | 0.83 | MAPT (0.34) | MAPTKDM4ETP53MAPK1CYP2C19 | |
| SCHEMBL8595151 | 0.79 | MAPT (0.32) | MAPTKDM4ETP53MAPK1CYP2C19 | |
| SCHEMBL4411371 | 0.78 | MAPT (0.31) | MAPTKDM4ETP53MAPK1CYP2C19 | |
| SCHEMBL11148288 | 0.78 | MAPT (0.31) | MAPTKDM4ETP53MAPK1CYP2C19 | |
| SCHEMBL11157363 | 0.76 | CES2 (0.38) | MAPTKDM4ETP53MAPK1CYP2C19 | |
| SCHEMBL9717843 | 0.76 | MAPT (0.38) | MAPTKDM4ETP53MAPK1CYP2C19 | |
| SCHEMBL11460849 | 0.75 | CES2 (0.43) | MAPTPTPN1ACP1CDC25BRECQL | |
| SCHEMBL57008 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1113827-A1 | POLYMER IMMOBILIZED LIVING CELLS AND APPLICATIONS THEREOF | HOLLAND BIOMATERIALS GROUP B.V. (NL) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000015272-A1 | POLYMER IMMOBILIZED LIVING CELLS AND APPLICATIONS THEREOF | HOLLAND BIOMATERIALS GROUP B.V. (NL) | 2000-03-23 | — | — | WO | disclosed |