Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19065143 | 1.00 | SMN1; SMN2 (0.32) | SMN1; SMN2HIF1ALNPEPNOS2 | |
| SCHEMBL19065141 | 1.00 | SMN1; SMN2 (0.32) | SMN1; SMN2HIF1ALNPEPNOS2 | |
| SCHEMBL4286857 | 0.82 | SMN1; SMN2 (0.35) | SMN1; SMN2HIF1A | |
| SCHEMBL894472 | 0.82 | SMN1; SMN2 (0.35) | SMN1; SMN2HIF1A | |
| Water SCHEMBL8680777 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2HIF1A | |
| SCHEMBL26092373 | 0.77 | BLM (0.31) | SMN1; SMN2HIF1A | |
| SCHEMBL59405 | 0.76 | BLM (0.47) | SMN1; SMN2HIF1A | |
| SCHEMBL163221 | 0.76 | BLM (0.47) | SMN1; SMN2HIF1A | |
| SCHEMBL59406 | 0.76 | BLM (0.47) | SMN1; SMN2HIF1A | |
| SCHEMBL1331226 | 0.76 | BLM (0.32) | SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2726495-A1 | METHOD FOR PREVENTING THE UNFOLDING OF A (POLY) PEPTIDE AND/OR INDUCING THE (RE- ) FOLDING OF A (POLY) PEPTIDE | LEUKOCARE AG (DE) | 2014-05-07 | — | — | EP | disclosed |
| WO-2013001044-A1 | METHOD FOR PREVENTING THE UNFOLDING OF A (POLY) PEPTIDE AND/OR INDUCING THE (RE- ) FOLDING OF A (POLY) PEPTIDE | LEUKOCARE AG (DE) | 2013-01-03 | — | — | WO | disclosed |
| EP-0436611-A4 | COMPOUND AND METHOD FOR THE RETARDATION OF COLLAGEN CROSS-LINKING | — | 1992-03-11 | — | — | EP | disclosed |
| EP-0436611-A1 | COMPOUND AND METHOD FOR THE RETARDATION OF COLLAGEN CROSS-LINKING | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1991-07-17 | — | — | EP | disclosed |
| WO-1990006102-A1 | COMPOUND AND METHOD FOR THE RETARDATION OF COLLAGEN CROSS-LINKING | PEPTIDE TECHNOLOGY LIMITED (AU) | 1990-06-14 | — | — | WO | disclosed |