Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717857 | 0.84 | ALDH1A1 (0.47) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11749020 | 0.83 | ALDH1A1 (0.57) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9717863 | 0.80 | ALDH1A1 (0.52) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL20239680 | 0.76 | ALDH1A1 (0.52) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28521894 | 0.75 | ALDH1A1 (0.55) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL25188015 | 0.74 | ALDH1A1 (0.50) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL12417061 | 0.74 | — | — | |
| SCHEMBL5483670 | 0.73 | — | — | |
| SCHEMBL14893122 | 0.72 | ALDH1A1 (0.47) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL891457 | 0.72 | ALDH1A1 (0.55) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253766-B1 | STABILIZED OLEFIN POLYMER INSULATING COMPOSITIONS | CIBA-GEIGY AG (CH) | 1992-03-11 | — | — | EP | disclosed |
| EP-0252878-B1 | VOLTAGE STABILIZED POLYOLEFIN COMPOSITIONS AND SILICONE-GLYCOL DERIVATIVES SUITABLE THEREFOR | CIBA-GEIGY AG (CH) | 1990-11-22 | — | — | EP | disclosed |
| US-4724248-A | POLYDIALKYLSILOXANEPOLYOXYALKYLENE BLOCK AND/OR GRAFT COPOLYMERS | CIBA-GEIGY CORPORATION (US) | 1988-02-09 | — | — | US | disclosed |
| EP-0253766-A2 | Stabilized olefin polymer insulating compositions | CIBA-GEIGY AG (CH) | 1988-01-20 | — | — | EP | disclosed |
| EP-0252878-A1 | Voltage stabilized polyolefin compositions and silicone-glycol derivatives suitable therefor | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |
| US-4689362-A | POLYSILOXANE POLYOXYALKYLENE BLOCK OR GRAFT COPOLYMERS AS STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1987-08-25 | — | — | US | disclosed |