Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717973 | 0.91 | KDM4E (0.49) | KDM4EALDH1A1PTAFR | |
| Hydrochloric Acid SCHEMBL9739377 | 0.90 | KDM4E (0.48) | KDM4EALDH1A1PTAFR | |
| SCHEMBL9737892 | 0.86 | KDM4E (0.50) | KDM4EALDH1A1PTAFR | |
| SCHEMBL9717899 | 0.83 | KDM4E (0.46) | KDM4EALDH1A1PTAFRNAMPT | |
| SCHEMBL9738331 | 0.82 | PTAFR (0.50) | KDM4EALDH1A1PTAFR | |
| Hydrochloric Acid SCHEMBL9717958 | 0.81 | PTAFR (0.49) | KDM4EALDH1A1PTAFR | |
| SCHEMBL9646308 | 0.79 | PTAFR (0.51) | KDM4EALDH1A1PTAFR | |
| SCHEMBL9717965 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1PTAFR | |
| SCHEMBL9717875 | 0.75 | NAMPT (0.45) | KDM4EALDH1A1PTAFRNAMPT | |
| Hydrochloric Acid SCHEMBL9717922 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019618-A1 | PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-11-12 | — | — | WO | claimed |
| WO-1992019618-A1 | PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5149704-A | Pyridyl- or thiazolidineaminesor ureas | ABBOTT LABORATORIES (US) | 1992-09-22 | — | — | US | disclosed |