Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | VNN1 | O95497 | 2/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PTAFR | P25105 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717898 | 0.91 | PTAFR (0.45) | NAMPTVNN1PTAFR | |
| Hydrochloric Acid SCHEMBL9717927 | 0.90 | PTAFR (0.44) | NAMPTVNN1PTAFR | |
| SCHEMBL9717904 | 0.86 | VNN1 (0.39) | NAMPTVNN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9717893 | 0.83 | ALDH1A1 (0.41) | NAMPTRAB9ATDP1ALDH1A1KDM4E | |
| SCHEMBL9738340 | 0.82 | TSHR (0.51) | NAMPTRAB9AL3MBTL1PTAFR | |
| Hydrochloric Acid SCHEMBL9717955 | 0.81 | TSHR (0.50) | NAMPTRAB9AL3MBTL1PTAFR | |
| SCHEMBL9646322 | 0.79 | PTAFR (0.47) | GALR3RAB9ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL9717971 | 0.75 | GRM2 (0.46) | ALDH1A1KDM4EHTTPTAFR | |
| SCHEMBL9717886 | 0.75 | KDM4E (0.52) | NAMPTALDH1A1KDM4EPTAFR | |
| Hydrochloric Acid SCHEMBL9717928 | 0.75 | GRM2 (0.46) | ALDH1A1KDM4EHTTPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019618-A1 | PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-11-12 | — | — | WO | claimed |
| WO-1992019618-A1 | PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5149704-A | Pyridyl- or thiazolidineaminesor ureas | ABBOTT LABORATORIES (US) | 1992-09-22 | — | — | US | disclosed |