Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9717948 | 0.99 | PTAFR (0.52) | PTAFRKDM4E | |
| SCHEMBL9717962 | 0.85 | PTAFR (0.47) | PTAFR | |
| SCHEMBL9717973 | 0.80 | KDM4E (0.49) | PTAFRKDM4E | |
| Hydrochloric Acid SCHEMBL9739377 | 0.79 | KDM4E (0.48) | PTAFRKDM4E | |
| SCHEMBL9717923 | 0.78 | PTAFR (0.49) | PTAFR | |
| SCHEMBL9646835 | 0.77 | PTAFR (0.54) | PTAFR | |
| SCHEMBL9739466 | 0.77 | PTAFR (0.49) | PTAFR | |
| SCHEMBL9718003 | 0.76 | PTAFR (0.46) | PTAFR | |
| SCHEMBL9646940 | 0.75 | PTAFR (0.50) | PTAFR | |
| Hydrochloric Acid SCHEMBL9717943 | 0.75 | PTAFR (0.45) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019618-A1 | PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-11-12 | — | — | WO | claimed |
| WO-1992019618-A1 | PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5149704-A | Pyridyl- or thiazolidineaminesor ureas | ABBOTT LABORATORIES (US) | 1992-09-22 | — | — | US | disclosed |