Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9717943 | 0.99 | PTAFR (0.45) | PTAFRGRM2 | |
| SCHEMBL9718007 | 0.76 | PTAFR (0.53) | PTAFR | |
| Hydrochloric Acid SCHEMBL9717948 | 0.75 | PTAFR (0.52) | PTAFR | |
| SCHEMBL9646273 | 0.74 | PTAFR (0.41) | PTAFR | |
| SCHEMBL9647005 | 0.73 | KDM4E (0.56) | — | |
| Hydrochloric Acid SCHEMBL9647770 | 0.72 | KDM4E (0.55) | — | |
| SCHEMBL9717965 | 0.72 | KDM4E (0.47) | PTAFRGRM2 | |
| Hydrochloric Acid SCHEMBL9717922 | 0.72 | KDM4E (0.47) | PTAFRGRM2 | |
| SCHEMBL9645118 | 0.71 | GRM2 (0.41) | PTAFRGRM2 | |
| SCHEMBL9250009 | 0.71 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019618-A1 | PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-11-12 | — | — | WO | claimed |
| WO-1992019618-A1 | PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5149704-A | Pyridyl- or thiazolidineaminesor ureas | ABBOTT LABORATORIES (US) | 1992-09-22 | — | — | US | disclosed |