SCHEMBL9718167

SCHEMBL9718167

O=C(O)CC(=O)c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.70
NR4A2 P43354 1/20 0.70
NR4A3 Q92570 1/20 0.70
MAOB P27338 1/20 0.66
PARP10 Q53GL7 1/20 0.66
SRD5A2 P31213 1/20 0.64
EGFR P00533 3/20 0.62
PLA2G4B P0C869 1/20 0.60
RAB9A P51151 3/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
ALDH1A1 P00352 2/20 0.60
MAPT P10636 2/20 0.60
GAA P10253 1/20 0.60
HTT P42858 1/20 0.60
FFAR1 O14842 1/20 0.59
FFAR4 Q5NUL3 1/20 0.59
NPC1 O15118 2/20 0.59
L3MBTL1 Q9Y468 1/20 0.58
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12987281 0.87 MAOB (0.71) NR4A1NR4A2NR4A3MAOBPARP10
SCHEMBL11683646 0.87 PTPN1 (0.72) NR4A1NR4A2NR4A3MAOBPARP10
SCHEMBL433676 0.86 MAOB (0.65) NR4A1NR4A2NR4A3MAOBPARP10
SCHEMBL958582 0.85 EGFR (0.69) NR4A1NR4A2NR4A3MAOBPARP10
SCHEMBL13427458 0.85 MEN1 (0.71) NR4A1NR4A2NR4A3MAOBPARP10
SCHEMBL1960673 0.85 NR4A1 (0.72) NR4A1NR4A2NR4A3MAOBPARP10
SCHEMBL4220632 0.85 NR4A1 (0.72) NR4A1NR4A2NR4A3MAOBPARP10
SCHEMBL2295339 0.84 BCHE (0.64) NR4A1NR4A2NR4A3MAOBPARP10
SCHEMBL29623581 0.84 NR4A1 (0.62) NR4A1NR4A2NR4A3MAOBPARP10
SCHEMBL8473200 0.84 NR4A1 (0.57) NR4A1NR4A2NR4A3MAOBPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0312604-B1 1-(2-(4-HYDROXYBENZOYL)ETHANOYL)-2-PIPERIDONE, PROCESS FOR ITS PREPARATION, AND ALCOHOLIC FERMENTATION ACCELERATOR CONTAINING IT AS EFFECTIVE INGREDIENT TAKI CHEMICAL CO., LTD. (JP) 1992-07-08 EP disclosed
EP-0312604-A4 1-(2-(4-HYDROXYBENZOYL)ETHANOYL)-2-PIPERIDONE, PROCESS FOR ITS PREPARATION, AND ALCOHOLIC FERMENTATION ACCELERATOR CONTAINING IT AS EFFECTIVE INGREDIENT. TAKI CHEMICAL (JP) 1990-06-26 EP disclosed
US-4908373-A 1-[2-(4-Hydroxybenzoyl)ethanoyl]-2-piperidone and a process for production as well as alcohol fermentation promoter containing the same as effective ingredient TAKI CHEMICAL CO., LTD. (JP) 1990-03-13 US disclosed
US-4908373-A 1-[2-(4-Hydroxybenzoyl)ethanoyl]-2-piperidone and a process for production as well as alcohol fermentation promoter containing the same as effective ingredient TAKI CHEMICAL CO., LTD. (JP) 1990-03-13 US disclosed
EP-0312604-A1 1-(2-(4-HYDROXYBENZOYL)ETHANOYL)-2-PIPERIDONE, PROCESS FOR ITS PREPARATION, AND ALCOHOLIC FERMENTATION ACCELERATOR CONTAINING IT AS EFFECTIVE INGREDIENT TAKI CHEMICAL CO., LTD. (JP) 1989-04-26 EP disclosed
EP-0312604-A1 1-(2-(4-HYDROXYBENZOYL)ETHANOYL)-2-PIPERIDONE, PROCESS FOR ITS PREPARATION, AND ALCOHOLIC FERMENTATION ACCELERATOR CONTAINING IT AS EFFECTIVE INGREDIENT TAKI CHEMICAL CO., LTD. (JP) 1989-04-26 EP disclosed
WO-1988008418-A1 1-(2-(4-HYDROXYBENZOYL)ETHANOYL)-2-PIPERIDONE, PROCESS FOR ITS PREPARATION, AND ALCOHOLIC FERMENTATION ACCELERATOR CONTAINING IT AS EFFECTIVE INGREDIENT TAKI CHEMICAL CO., LTD. (JP) 1988-11-03 WO disclosed