Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.62 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 4/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800190 | 0.89 | EGFR (0.61) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL7800185 | 0.87 | NR4A1 (0.57) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL9718167 | 0.84 | NR4A1 (0.70) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL11683646 | 0.82 | PTPN1 (0.72) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL12987281 | 0.82 | MAOB (0.71) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL4113161 | 0.81 | NR4A2 (0.70) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL1115991 | 0.81 | NR4A1 (0.60) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL433676 | 0.81 | MAOB (0.65) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL1953538 | 0.81 | KMT2A (0.64) | NR4A2RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1960673 | 0.80 | NR4A1 (0.72) | NR4A1NR4A2NR4A3MAOBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986875-A1 | PHENOXYPHENYL HYDROXYISOXAZOLINES AND ANALOGUES AS NEW ANTIFUNGAL AGENTS | Bayer Aktiengesellschaft (DE) | 2022-04-27 | — | — | EP | disclosed |