SCHEMBL9718232

SCHEMBL9718232

CC1(C)CN(CC(Nc2nc(NC(CN3CC(C)(C)NC(C)(C)C3=O)C3CCCCC3)nc(NC(CN3CC(C)(C)NC(C)(C)C3=O)C3CCCCC3)n2)C2CCCCC2)C(=O)C(C)(C)N1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11096985 0.95 PDE4A (0.33)
SCHEMBL11093486 0.90 ALDH1A1 (0.35)
SCHEMBL11096636 0.89 PDE4A (0.31)
SCHEMBL11093217 0.86 MAPK1 (0.36)
SCHEMBL11094052 0.81
SCHEMBL11117685 0.81
SCHEMBL31745564 0.78 ALDH1A1 (0.31)
SCHEMBL11094651 0.76
SCHEMBL10486753 0.76 ALDH1A1 (0.30)
SCHEMBL11130042 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142001-A Neutralization of a polyurethane containing hydrophilic acidic group with piperidine compound KYOWA HAKKO KOGYO CO., LTD. (JP) 1992-08-25 US claimed
US-5142001-A Neutralization of a polyurethane containing hydrophilic acidic group with piperidine compound KYOWA HAKKO KOGYO CO., LTD. (JP) 1992-08-25 US disclosed
EP-0101735-A4 SUBSTITUTED OXO-PIPERAZINYL-TRIAZINES AND UV LIGHT STABILIZED COMPOSITIONS. GOODRICH CO B F (US) 1984-06-29 EP disclosed
EP-0101735-A1 SUBSTITUTED OXO-PIPERAZINYL-TRIAZINES AND UV LIGHT STABILIZED COMPOSITIONS. GOODRICH CO B F (US) 1984-03-07 EP disclosed
WO-1983002943-A1 ALKYLATED POLYALKYLENEPOLYAMINES, SUBSTITUTED OXO-PIPERAZINYL-TRIAZINES AND UV LIGHT STABILIZED COMPOSITIONS GOODRICH CO B F (US) 1983-09-01 WO disclosed