Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 6/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.50 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628657 | 0.94 | TSHR (0.45) | BIDMCL1BCL2L1BAK1TSHR | |
| SCHEMBL10629844 | 0.94 | TSHR (0.45) | BIDMCL1BCL2L1BAK1TSHR | |
| SCHEMBL1985933 | 0.91 | BID (0.60) | BIDMCL1BCL2L1BAK1TSHR | |
| SCHEMBL4627298 | 0.88 | ALDH1A1 (0.53) | BIDMCL1BCL2L1BAK1TSHR | |
| SCHEMBL4627873 | 0.88 | TSHR (0.45) | BIDMCL1BCL2L1BAK1TSHR | |
| SCHEMBL11582383 | 0.88 | TSHR (0.62) | BIDMCL1BCL2L1BAK1TSHR | |
| SCHEMBL9568678 | 0.88 | TSHR (0.62) | BIDMCL1BCL2L1BAK1TSHR | |
| SCHEMBL21225342 | 0.88 | TSHR (0.62) | BIDMCL1BCL2L1BAK1TSHR | |
| SCHEMBL28854776 | 0.88 | TSHR (0.62) | BIDMCL1BCL2L1BAK1TSHR | |
| SCHEMBL2045733 | 0.88 | TSHR (0.62) | BIDMCL1BCL2L1BAK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473915-A1 | Improved barrier PVC resins, compounds and articles derived therefrom | THE B.F. GOODRICH COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |
| EP-0358181-A2 | Polyvinyl chloride blends having improved physical properties | The Geon Company (US) | 1990-03-14 | — | — | EP | disclosed |