Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | BAD | Q92934 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891562 | 0.90 | POLB (0.55) | POLBSRD5A2MAPK1MAPTELANE | |
| SCHEMBL7841315 | 0.88 | SRD5A2 (0.60) | POLBSRD5A2MAPK1MAPTELANE | |
| SCHEMBL10880512 | 0.84 | POLB (0.46) | POLBSRD5A2MAPK1MAPTPARP10 | |
| SCHEMBL10448654 | 0.83 | SRD5A2 (0.62) | POLBSRD5A2BCL2MCL1ELANE | |
| SCHEMBL9419499 | 0.83 | SRD5A2 (0.58) | POLBSRD5A2MAPK1MAPTELANE | |
| SCHEMBL1081660 | 0.83 | SRD5A2 (0.72) | POLBSRD5A2MAPK1ELANEPARP10 | |
| SCHEMBL26624065 | 0.83 | SRD5A2 (0.72) | POLBSRD5A2MAPK1ELANEPARP10 | |
| SCHEMBL10593556 | 0.83 | SRD5A2 (0.72) | POLBSRD5A2MAPK1ELANEPARP10 | |
| SCHEMBL234249 | 0.83 | SRD5A2 (0.84) | POLBSRD5A2ELANEPARP10ALDH1A1 | |
| SCHEMBL1069817 | 0.83 | SRD5A2 (0.84) | POLBSRD5A2ELANEPARP10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463058-A1 | PROCESS FOR THE MANUFACTURE OF 1,4-BIS(4-PHENOXYBENZOYL)BENZENE WITH CERTAIN METAL-CONTAINING CATALYSTS. | DU PONT (US) | 1992-01-02 | — | — | EP | disclosed |
| WO-1990010613-A1 | PROCESS FOR THE MANUFACTURE OF 1,4-BIS(4-PHENOXYBENZOYL)BENZENE WITH CERTAIN METAL-CONTAINING CATALYSTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-09-20 | — | — | WO | disclosed |