SCHEMBL7841315

SCHEMBL7841315

O=C(O)c1ccc(Oc2cc(C(=O)O)ccc2C(=O)c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 0.60
POLB P06746 1/20 0.59
KDM4E B2RXH2 1/20 0.58
TTR P02766 2/20 0.55
CYP2C8 P10632 1/20 0.54
CYP2C9 P11712 1/20 0.54
MAPK1 P28482 2/20 0.54
MAPT P10636 1/20 0.54
AKR1C3 P42330 1/20 0.51
ALDH1A1 P00352 2/20 0.50
ELANE P08246 1/20 0.49
LMNA P02545 1/20 0.48
CYP1A2 P05177 1/20 0.48
PGR P06401 1/20 0.48
CYP2D6 P10635 1/20 0.48
HPGD P15428 1/20 0.48
SLC6A2 P23975 1/20 0.48
PDE4A P27815 1/20 0.48
CYP2C19 P33261 1/20 0.48
HRH1 P35367 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7841316 0.90 MAPK1 (0.61) SRD5A2POLBKDM4ETTRCYP2C8
SCHEMBL9718282 0.88 POLB (0.63) SRD5A2POLBMAPK1MAPTALDH1A1
SCHEMBL28331260 0.87 SRD5A2 (0.64) SRD5A2POLBKDM4ETTRCYP2C8
SCHEMBL11322194 0.85 TTR (0.54) SRD5A2POLBKDM4ETTRAKR1C3
SCHEMBL30497476 0.85 TTR (0.54) SRD5A2POLBKDM4ETTRAKR1C3
SCHEMBL28891562 0.84 POLB (0.55) SRD5A2POLBKDM4EMAPK1MAPT
SCHEMBL649980 0.83 TTR (0.66) SRD5A2POLBKDM4ETTRAKR1C3
Hydrochloric Acid SCHEMBL9672161 0.83 TTR (0.60) SRD5A2POLBKDM4ETTRAKR1C3
Hydrochloric Acid SCHEMBL10485517 0.82 TTR (0.64) SRD5A2POLBKDM4ETTRAKR1C3
Hydrochloric Acid SCHEMBL28567730 0.82 TTR (0.64) SRD5A2POLBKDM4ETTRAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1138092-A1 COMPOSITE BODIES USED AS SEPARATORS IN ELECTROCHEMICAL CELLS BASF AKTIENGESELLSCHAFT (DE) 2001-10-04 EP disclosed
WO-2000026977-A1 COMPOSITE BODIES USED AS SEPARATORS IN ELECTROCHEMICAL CELLS BASF AKTIENGESELLSCHAFT (DE) 2000-05-11 WO disclosed