Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096041 | 0.91 | PPARA (0.59) | TSHRHTR2AHTR2CHTR2BPPARA | |
| Rac-Dichlorprop SCHEMBL1496084 | 0.87 | TSHR (0.88) | TSHRHTR2AHTR2CHTR2BPPARA | |
| SCHEMBL11712419 | 0.86 | TSHR (0.72) | TSHRHTR2AHTR2CHTR2BTRPM4 | |
| SCHEMBL11716051 | 0.84 | SMN1; SMN2 (0.54) | TSHRHTR2AHTR2CHTR2BPPARA | |
| SCHEMBL4482051 | 0.82 | TSHR (0.62) | TSHRHTR2AHTR2CHTR2BPPARA | |
| SCHEMBL11752192 | 0.81 | TSHR (0.73) | TSHRHTR2AHTR2CHTR2BPPARA | |
| SCHEMBL17780865 | 0.80 | TSHR (0.71) | TSHRHTR2AHTR2CHTR2BPPARA | |
| Mecoprop-P SCHEMBL572351 | 0.80 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BTRPM4 | |
| Mecoprop SCHEMBL7762943 | 0.80 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BTRPM4 | |
| SCHEMBL8339820 | 0.80 | TSHR (0.71) | TSHRHTR2AHTR2CHTR2BPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169425-A | Synergistic mixture | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-12-08 | — | — | US | disclosed |