SCHEMBL28096041

SCHEMBL28096041

O=C(O)C(Oc1ccc(Cl)cc1Cl)C(Oc1ccc(Cl)cc1Cl)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.59
TDP1 Q9NUW8 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.51
TSHR P16473 3/20 0.50
HTR2A P28223 1/20 0.50
HTR2C P28335 1/20 0.50
HTR2B P41595 1/20 0.50
HPGD P15428 3/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
GLA P06280 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
ALOX12 P18054 1/20 0.49
RECQL P46063 1/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
GAA P10253 1/20 0.48
TTR P02766 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9718320 0.91 TSHR (0.66) PPARATDP1SMN1; SMN2TSHRHTR2A
SCHEMBL11716051 0.90 SMN1; SMN2 (0.54) PPARATDP1SMN1; SMN2TSHRHTR2A
SCHEMBL11593869 0.85 PPARA (0.59) PPARATDP1SMN1; SMN2TSHRHTR2A
SCHEMBL23632886 0.84 PPARA (0.57) PPARATDP1SMN1; SMN2TSHRHTR2A
SCHEMBL11573118 0.84 PPARA (0.57) PPARATDP1SMN1; SMN2TSHRHTR2A
SCHEMBL25285997 0.83 SMN1; SMN2 (0.48) PPARATDP1SMN1; SMN2TSHRHTR2A
SCHEMBL2463704 0.82 PPARA (0.50) PPARATDP1SMN1; SMN2TSHRHTR2A
Rac-Dichlorprop SCHEMBL54510 0.82 TSHR (0.73) PPARASMN1; SMN2TSHRHTR2AHTR2C
(S)-Dichlorprop SCHEMBL1535831 0.82 TSHR (0.73) PPARASMN1; SMN2TSHRHTR2AHTR2C
(R)-Dichlorprop SCHEMBL55175 0.82 TSHR (0.73) PPARASMN1; SMN2TSHRHTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118159657-A Rice cytoplasmic male sterility restoring gene OsRf and application thereof 华中农业大学 2024-06-07 CN disclosed
CN-116004658-B Application of tomato SlERF.H6 gene in regulating and controlling solanine metabolism to reduce tomato toxicity 海南大学 2024-03-08 CN disclosed
CN-116121266-B Application of rice gene qSS7 in drought resistance 华中农业大学 2024-02-27 CN disclosed
CN-117587058-A Application of rice gene DRT6 in drought resistance 华中农业大学 2024-02-23 CN disclosed
CN-115820669-B Application of SlGA2ox gene in regulating tomato toxic alkaloid content 海南大学 2024-02-20 CN disclosed
CN-115991754-B Method for restoring rice fertility by pf12A gene and application of method in regulation and control of rice fertility 华中农业大学 2024-02-20 CN disclosed
CN-117535344-A Application of rice auxin receptor gene OsTIR1in influencing rice quality 南京农业大学 2024-02-09 CN disclosed
CN-114181949-B Application of tomato SlERF063 gene in promoting fruit ripening and reducing fruit toxicity 海南大学 2024-01-30 CN disclosed
CN-117448357-A Application of rice gene qTSS1 in improving rice taste quality 华中农业大学 2024-01-26 CN disclosed
CN-117070527-A Application of rice gene HL6 in regulation and control of diterpene plant protection element content and enhancement of disease resistance 华中农业大学 2023-11-17 CN disclosed
CN-116254272-A Application of gene OsPIN10b in plant root elongation 河南农业大学 2023-06-13 CN disclosed
CN-114480421-B Rice photosensitive pigment protein mutant gene OsPHYA and application thereof 南京农业大学 2023-05-26 CN disclosed
CN-116121266-A Application of rice gene qSS7 in drought resistance 华中农业大学 2023-05-16 CN disclosed
CN-116004658-A Application of tomato SlERF.H6 gene in regulating and controlling solanine metabolism to reduce tomato toxicity 海南大学 2023-04-25 CN disclosed
CN-115991754-A Method for restoring rice fertility by pf12A gene and application of method in regulation and control of rice fertility 华中农业大学 2023-04-21 CN disclosed
CN-110747203-B Application of gene OsBBX14 in improving bacterial leaf blight resistance of rice 山东省水稻研究所 2022-05-06 CN disclosed
CN-110747203-A Application of gene OsBBX14 in improving resistance to rice bacterial blight 山东省水稻研究所 2020-02-04 CN disclosed
CN-106550875-B For the MS culture mediums of rouge radish tissue cultures, the quick breeding method for tissue culture of adventitious shoots culture base and rouge radish 长江师范学院 2018-09-28 CN disclosed
CN-106550875-A For the quick breeding method for tissue culture of the MS culture medium, adventitious shoots culture base and rouge radish of rouge radish tissue culture 长江师范学院 2017-04-05 CN disclosed
CN-105924265-A Flowering phase extender and method for extending flowering phase by using same 江西农业大学 2016-09-07 CN disclosed