Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | CDC25B | P30305 | 2/20 | 0.59 |
| ▸ | CDC25A | P30304 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 2/20 | 0.50 |
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717002 | 0.93 | CDC25B (0.64) | KDM4ECDC25BCDC25AHSD17B10ALDH1A1 | |
| SCHEMBL8962328 | 0.88 | CDC25B (0.77) | KDM4ECDC25BCDC25AHSD17B10ALDH1A1 | |
| SCHEMBL9721182 | 0.88 | ALDH1A1 (0.62) | KDM4ECDC25BCDC25AHSD17B10ALDH1A1 | |
| SCHEMBL9721168 | 0.88 | CDC25B (0.61) | KDM4ECDC25BCDC25AHSD17B10ALDH1A1 | |
| SCHEMBL2058646 | 0.88 | KDM4E (0.79) | KDM4ECDC25BCDC25AHSD17B10ALDH1A1 | |
| SCHEMBL5151518 | 0.84 | ALDH1A1 (0.75) | CDC25BCDC25AHSD17B10ALDH1A1NR4A1 | |
| SCHEMBL31304680 | 0.84 | ALDH1A1 (0.75) | CDC25BCDC25AHSD17B10ALDH1A1NR4A1 | |
| SCHEMBL5311692 | 0.84 | KDM4E (0.77) | KDM4ECDC25BCDC25AHSD17B10ALDH1A1 | |
| SCHEMBL160657 | 0.83 | SRD5A2 (0.71) | KDM4ECDC25BCDC25AHSD17B10ALDH1A1 | |
| Phthalic Acid SCHEMBL20678581 | 0.82 | CDC25B (0.77) | KDM4ECDC25BCDC25AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499451-A1 | Synthesis of 1-amino-anthraquinone | HOECHST CELANESE CORPORATION (US) | 1992-08-19 | — | — | EP | claimed |
| US-5132437-A | From 2-Substituted Benzyl Compound and Xylene | HOECHST CELANESE CORPORATION (US) | 1992-07-21 | — | — | US | claimed |
| EP-0499451-A1 | Synthesis of 1-amino-anthraquinone | HOECHST CELANESE CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| US-5132437-A | From 2-Substituted Benzyl Compound and Xylene | HOECHST CELANESE CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |