SCHEMBL9718476

SCHEMBL9718476

CC(C)N(c1ccc(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1)C(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.37
HSD11B1 P28845 2/20 0.36
ALDH1A1 P00352 3/20 0.35
CYP2D6 P10635 3/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NR1H2 P55055 2/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
CYP3A4 P08684 2/20 0.33
NPC1 O15118 1/20 0.33
PLA2G1B P04054 1/20 0.33
NFKB1 P19838 1/20 0.33
CASP3 P42574 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24703343 0.80 TSHR (0.44) ALDH1A1HSD17B10NPC1PLA2G1BNFKB1
SCHEMBL141145 0.79 ALDH1A1 (0.42) ALDH1A1ESR1MLYCDMEN1KMT2A
SCHEMBL28390686 0.77 ALDH1A1 (0.41) ALDH1A1ESR1MEN1KMT2A
Hydrochloric Acid SCHEMBL29160785 0.77 ALDH1A1 (0.41) ALDH1A1ESR1MEN1KMT2A
SCHEMBL184934 0.77 ALDH1A1 (0.41) ALDH1A1ESR1MLYCDMEN1KMT2A
SCHEMBL20438385 0.76 ALDH1A1 (0.39) ALDH1A1HSD17B10CYP3A4MAPK1
SCHEMBL11239568 0.76 ESR1 (0.35) KCNN4ALDH1A1CYP2D6CYP2C19HSD17B10
SCHEMBL5922062 0.76 SLC2A1 (0.54) KCNN4ALDH1A1HSD17B10CYP3A4NPC1
SCHEMBL10775477 0.76 SLC2A1 (0.54) KCNN4ALDH1A1HSD17B10CYP3A4NPC1
SCHEMBL9780514 0.76 SLC2A1 (0.54) KCNN4ALDH1A1HSD17B10CYP3A4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5080989-A Polycarbonate, solvent resistance EASTMAN KODAK COMPANY (US) 1992-01-14 US disclosed
US-4361636-A COLORANT EASTMAN KODAK COMPANY (US) 1982-11-30 US disclosed
EP-0064007-A1 Ionic polyesters, electrically photosensitive composite particles and materials containing the polyesters and photoelectrophoretic imaging methods EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-11-03 EP disclosed
US-4322487-A Composite electrically photosensitive particles for electrophoretic migration imaging process EASTMAN KODAK COMPANY (US) 1982-03-30 US disclosed