Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685097 | 0.92 | RIPK1 (0.56) | RIPK1HSPA5LMNACYP2D6TAAR1 | |
| SCHEMBL6547278 | 0.86 | HTR2A (0.50) | RIPK1LMNACYP2D6TAAR1SLC6A2 | |
| SCHEMBL6685032 | 0.82 | RIPK1 (0.48) | RIPK1CYP2D6TAAR1SLC6A2ESR1 | |
| SCHEMBL13334563 | 0.81 | SLC6A4 (0.46) | RIPK1LMNACYP2D6TAAR1SLC6A2 | |
| SCHEMBL396630 | 0.80 | RIPK1 (0.47) | RIPK1TAAR1SLC6A2ESR1 | |
| SCHEMBL358741 | 0.80 | RIPK1 (0.47) | RIPK1LMNACYP2D6TAAR1SLC6A2 | |
| SCHEMBL21711085 | 0.80 | RIPK1 (0.47) | RIPK1LMNACYP2D6TAAR1SLC6A2 | |
| SCHEMBL13630822 | 0.80 | RIPK1 (0.47) | RIPK1LMNACYP2D6TAAR1SLC6A2 | |
| SCHEMBL10318075 | 0.80 | RIPK1 (0.47) | RIPK1LMNACYP2D6TAAR1SLC6A2 | |
| SCHEMBL13020681 | 0.80 | RIPK1 (0.47) | RIPK1LMNACYP2D6TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016537-A1 | ALKYL-AROMATIC DIPHOSPHITES | ETHYL CORPORATION (US) | 1992-10-01 | — | — | WO | claimed |