Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 2/20 | 0.93 |
| ▸ | CA12 | O43570 | 5/20 | 0.80 |
| ▸ | CA6 | P23280 | 5/20 | 0.80 |
| ▸ | CA7 | P43166 | 5/20 | 0.80 |
| ▸ | CA9 | Q16790 | 5/20 | 0.80 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.80 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.80 |
| ▸ | CA2 | P00918 | 4/20 | 0.80 |
| ▸ | CA4 | P22748 | 4/20 | 0.80 |
| ▸ | CA5A | P35218 | 4/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.80 |
| ▸ | F13A1 | P00488 | 2/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.80 |
| ▸ | THPO | P40225 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | RECQL | P46063 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.80 |
| ▸ | CA3 | P07451 | 3/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718696 | 1.00 | CASP2 (0.93) | CASP2CA12CA6CA7CA9 | |
| SCHEMBL9302439 | 1.00 | CASP2 (0.93) | CASP2CA12CA6CA7CA9 | |
| Thermine SCHEMBL8837088 | 1.00 | CASP2 (0.93) | CASP2CA12CA6CA7CA9 | |
| SCHEMBL19179132 | 1.00 | CASP2 (0.93) | CASP2CA12CA6CA7CA9 | |
| SCHEMBL11365907 | 0.97 | CASP2 (0.87) | CASP2CA12CA6CA7CA9 | |
| SCHEMBL19257489 | 0.97 | CASP2 (0.87) | CASP2CA12CA6CA7CA9 | |
| SCHEMBL869794 | 0.96 | CA12 (0.86) | CASP2CA12CA6CA7CA9 | |
| SCHEMBL561809 | 0.96 | CA12 (0.86) | CASP2CA12CA6CA7CA9 | |
| SCHEMBL3062038 | 0.96 | CASP2 (1.00) | CASP2CA12CA6CA7CA9 | |
| SCHEMBL3159043 | 0.96 | CA12 (0.86) | CASP2CA12CA6CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4569750-A | MACROCYCLIC POLYAMINES | EXXON RESEARCH & ENGINEERING CO. (US) | 1986-02-11 | — | — | US | claimed |
| US-4312999-A | ANTIFOULING AGENTS IN WATER SYSTEMS | ASHLAND OIL, INC. (US) | 1982-01-26 | — | — | US | claimed |
| US-4247404-A | Glyoxal-polyamine-polybutenyl succinic anhydride reaction products, process for their preparation and lubricants and fuels containing same | ASHLAND OIL, INC. (US) | 1981-01-27 | — | — | US | claimed |
| US-5162526-A | Dispersants, fuel additives | EXXON CHEMICAL PATENTS INC. (US) | 1992-11-10 | — | — | US | disclosed |
| US-4637886-A | Macrocyclic polyamine and polycyclic polyamine multifunctional lubricating oil additives | EXXON RESEARCH & ENGINEERING CO. (US) | 1987-01-20 | — | — | US | disclosed |
| US-4569750-A | MACROCYCLIC POLYAMINES | EXXON RESEARCH & ENGINEERING CO. (US) | 1986-02-11 | — | — | US | disclosed |
| EP-0053571-B1 | PURIFICATION OF HYDROCARBONS BY TREATMENT WITH POLYAMINES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4401838-A | Purification of hydrocarbons by treatment with polyamines | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-08-30 | — | — | US | disclosed |
| US-4337154-A | FORMED FROM A POLYALKYLENIMINE AND A NITROGEN-HETEROCYCLIC SECONDARY AMINE COMPOUND | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0053571-A1 | Purification of hydrocarbons by treatment with polyamines | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-06-09 | — | — | EP | disclosed |
| US-4312999-A | ANTIFOULING AGENTS IN WATER SYSTEMS | ASHLAND OIL, INC. (US) | 1982-01-26 | — | — | US | disclosed |
| US-4247404-A | Glyoxal-polyamine-polybutenyl succinic anhydride reaction products, process for their preparation and lubricants and fuels containing same | ASHLAND OIL, INC. (US) | 1981-01-27 | — | — | US | disclosed |