Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718799 | 0.89 | KCNH2 (0.52) | KCNH2SETD7PTAFRTP53PRMT5 | |
| SCHEMBL9718730 | 0.88 | SETD7 (0.51) | KCNH2SETD7MAPK1PTAFRPRMT5 | |
| Hydrochloric Acid SCHEMBL9718840 | 0.88 | KCNH2 (0.51) | KCNH2SETD7PTAFRTP53PRMT5 | |
| Hydrochloric Acid SCHEMBL9718776 | 0.85 | KCNH2 (0.49) | KCNH2SETD7GLAMAPK1KDM4E | |
| SCHEMBL9850651 | 0.84 | KCNH2 (0.51) | KCNH2SETD7GLAKDM4EALDH1A1 | |
| SCHEMBL9850495 | 0.83 | KCNH2 (0.52) | KCNH2SETD7GLAMAPK1KDM4E | |
| SCHEMBL13888720 | 0.82 | KCNH2 (0.52) | KCNH2SETD7GLAMAPK1KDM4E | |
| SCHEMBL9718787 | 0.81 | SETD7 (0.57) | KCNH2SETD7KDM4EALDH1A1GAA | |
| SCHEMBL9718791 | 0.81 | KCNH2 (0.56) | KCNH2SETD7MAPK1KDM4EALDH1A1 | |
| SCHEMBL11601728 | 0.80 | KCNH2 (0.53) | KCNH2SETD7GLAPTAFRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095022-A | Antiallergens | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |
| EP-0406739-A2 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |