Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850495 | 0.89 | KCNH2 (0.52) | KCNH2SETD7RXFP1KDM4ENPC1 | |
| SCHEMBL9718747 | 0.85 | KCNH2 (0.51) | KCNH2SETD7RXFP1KDM4ENPC1 | |
| SCHEMBL9718757 | 0.84 | KCNH2 (0.49) | KCNH2SETD7RXFP1KDM4ENPC1 | |
| SCHEMBL9718775 | 0.83 | KCNH2 (0.52) | KCNH2SETD7RXFP1KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL9718756 | 0.83 | KCNH2 (0.49) | KCNH2SETD7RXFP1KDM4ENPC1 | |
| SCHEMBL9718799 | 0.82 | KCNH2 (0.52) | KCNH2SETD7RXFP1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9718801 | 0.82 | KCNH2 (0.52) | KCNH2SETD7RXFP1KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL9718718 | 0.82 | KCNH2 (0.48) | KCNH2SETD7RXFP1KDM4ENPC1 | |
| SCHEMBL14559374 | 0.82 | SETD7 (0.54) | KCNH2SETD7RXFP1NPC1RAB9A | |
| SCHEMBL11600344 | 0.81 | KCNH2 (0.55) | KCNH2SETD7RXFP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406739-A2 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |