Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.60 |
| ▸ | RAB9A | P51151 | 11/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 10/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | PRNP | P04156 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4915377 | 0.83 | MAPT (0.59) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4916241 | 0.83 | DYRK1A (0.56) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4915371 | 0.82 | MAPT (0.58) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4908696 | 0.82 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4921098 | 0.82 | PKM (0.60) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4908655 | 0.80 | GAA (0.50) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4919280 | 0.80 | MAPT (0.48) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4919944 | 0.79 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4915044 | 0.79 | SMN1; SMN2 (0.55) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4913870 | 0.79 | TRPV1 (0.47) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151472-A | Dissolving polyetherimides in a solvent, adding a dianhydride and a diamine, reacting to form a polyamic acid and cyclizing to form a polyimide | GENERAL DYNAMICS CORPORATION, CONVAIR DIVISION (US) | 1992-09-29 | — | — | US | disclosed |