Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18410602 | 0.82 | PIM1 (0.49) | PIM1AKR1C3GAALMNAHTT | |
| SCHEMBL9081346 | 0.82 | MEN1 (0.46) | GAALMNAGFERTAAR1MEN1 | |
| SCHEMBL8573943 | 0.82 | MEN1 (0.53) | PIM1AKR1C3GAALMNAHTT | |
| SCHEMBL18236212 | 0.82 | PIM1 (0.49) | PIM1AKR1C3GAALMNAHTT | |
| SCHEMBL18233013 | 0.78 | PIM1 (0.46) | PIM1AKR1C3GAALMNAHTT | |
| SCHEMBL2927614 | 0.76 | AKR1C3 (0.49) | PIM1AKR1C3GAALMNAHTT | |
| SCHEMBL30020996 | 0.75 | MEN1 (0.75) | AKR1C3GAALMNAMEN1KMT2A | |
| SCHEMBL239690 | 0.75 | MEN1 (0.75) | AKR1C3GAALMNAMEN1KMT2A | |
| SCHEMBL5312503 | 0.74 | MAPT (0.51) | PIM1AKR1C3GAALMNAHTT | |
| SCHEMBL9718855 | 0.73 | PIM1 (0.50) | PIM1AKR1C3GAALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151472-A | Dissolving polyetherimides in a solvent, adding a dianhydride and a diamine, reacting to form a polyamic acid and cyclizing to form a polyimide | GENERAL DYNAMICS CORPORATION, CONVAIR DIVISION (US) | 1992-09-29 | — | — | US | disclosed |