Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10209516 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2HPGDMEN1KMT2AHTT | |
| SCHEMBL21991382 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL31096135 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL21823680 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL13813328 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7942502 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27825522 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29732515 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1627615 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL12440953 | 0.78 | KDM4E (0.42) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257921-B1 | NEW 1,3-DIARYL CYCLOPENTANES AND DERIVATIVES THEREOF AS PAF ANTAGONISTS | MERCK & CO. INC. (US) | 1992-04-15 | — | — | EP | disclosed |