Phosphoric Acid

Phosphoric Acid

SCHEMBL9719166

CCCNCCCCCNc1cc(OC)cc2cccnc12.O=P(O)(O)O

nearest known ligand 0.65

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 8/20 0.65
HSP90AB1 P08238 8/20 0.65
KMT2A Q03164 5/20 0.63
MEN1 O00255 4/20 0.63
ALDH1A1 P00352 3/20 0.63
HTT P42858 2/20 0.63
TP53 P04637 1/20 0.63
KDM4E B2RXH2 3/20 0.58
THRB P10828 2/20 0.58
MAPT P10636 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
TDP2 O95551 1/20 0.58
FGB P02675 1/20 0.58
POLB P06746 1/20 0.58
GAA P10253 1/20 0.58
TSHR P16473 1/20 0.58
NR4A1 P22736 1/20 0.58
RECQL P46063 1/20 0.58
RAB9A P51151 1/20 0.58
BLM P54132 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18163920 0.87 HSP90AA1 (0.80) HSP90AA1HSP90AB1KMT2AMEN1ALDH1A1
Pentaquine SCHEMBL6081373 0.86 HSP90AA1 (0.67) HSP90AA1HSP90AB1KMT2AMEN1ALDH1A1
SCHEMBL13856507 0.85 HSP90AA1 (0.80) HSP90AA1HSP90AB1KMT2AMEN1ALDH1A1
Quinocide SCHEMBL2286358 0.82 MEN1 (0.88) HSP90AA1HSP90AB1KMT2AMEN1ALDH1A1
SCHEMBL8891233 0.80 HSP90AA1 (0.98) HSP90AA1HSP90AB1KMT2AMEN1ALDH1A1
SCHEMBL8891533 0.80 HSP90AA1 (0.98) HSP90AA1HSP90AB1KMT2AMEN1ALDH1A1
SCHEMBL8891243 0.80 HSP90AA1 (0.98) HSP90AA1HSP90AB1KMT2AMEN1ALDH1A1
SCHEMBL8900580 0.80 HSP90AA1 (0.98) HSP90AA1HSP90AB1KMT2AMEN1ALDH1A1
Hydrochloric Acid SCHEMBL11410128 0.79 HSP90AA1 (0.95) HSP90AA1HSP90AB1KMT2AMEN1ALDH1A1
SCHEMBL8893299 0.79 HSP90AA1 (1.00) HSP90AA1HSP90AB1KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5104885-A 5-(phenylalkoxy)primaquine and 5[(heterocycle)alkoxy] primaquine compounds and their use for treatment of malaria CALSPAN CORPORATION (US) 1992-04-14 US disclosed
US-4980360-A NONTOXIC AT HIGHER DOSAGES CALSPAN CORPORATION (US) 1990-12-25 US disclosed
US-4554279-A PLASMODICIDAL THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1985-11-19 US disclosed