Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 4/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 3/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482499 | 1.00 | HCAR2 (0.48) | HCAR2CYP19A1KEAP1NFE2L2TSHR | |
| SCHEMBL11741771 | 1.00 | HCAR2 (0.48) | HCAR2CYP19A1KEAP1NFE2L2TSHR | |
| SCHEMBL3516990 | 0.93 | HCAR2 (0.59) | HCAR2CYP19A1KEAP1NFE2L2TSHR | |
| SCHEMBL5848513 | 0.91 | HCAR2 (0.63) | HCAR2TSHRLAP3RNPEPSLC7A5 | |
| SCHEMBL3482497 | 0.91 | HCAR2 (0.63) | HCAR2TSHRLAP3RNPEPSLC7A5 | |
| SCHEMBL7778545 | 0.91 | HCAR2 (0.42) | HCAR2CYP19A1KEAP1NFE2L2TSHR | |
| SCHEMBL3482501 | 0.91 | HCAR2 (0.63) | HCAR2TSHRLAP3RNPEPSLC7A5 | |
| SCHEMBL23116186 | 0.89 | HCAR2 (0.39) | HCAR2CYP19A1TSHRLAP3RNPEP | |
| SCHEMBL273808 | 0.89 | HCAR2 (0.39) | HCAR2CYP19A1TSHRLAP3RNPEP | |
| SCHEMBL273806 | 0.89 | HCAR2 (0.39) | HCAR2CYP19A1TSHRLAP3RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142009-A | Crosslinked blend of fumaric acid diesters | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-4868260-A | OXYGEN PERMEABILITY | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1989-09-19 | — | — | US | disclosed |