Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 4/20 | 0.31 |
| ▸ | ANPEP | P15144 | 3/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273806 | 1.00 | HCAR2 (0.39) | HCAR2CYP19A1MMP1MMP2MMP3 | |
| SCHEMBL273808 | 1.00 | HCAR2 (0.39) | HCAR2CYP19A1MMP1MMP2MMP3 | |
| SCHEMBL3482499 | 0.89 | HCAR2 (0.48) | HCAR2CYP19A1MMP1MMP2MMP3 | |
| SCHEMBL9719175 | 0.89 | HCAR2 (0.48) | HCAR2CYP19A1MMP1MMP2MMP3 | |
| SCHEMBL11741771 | 0.89 | HCAR2 (0.48) | HCAR2CYP19A1MMP1MMP2MMP3 | |
| SCHEMBL15855993 | 0.86 | HCAR2 (0.35) | HCAR2MMP1MMP2MMP3MMP9 | |
| SCHEMBL15855994 | 0.86 | HCAR2 (0.35) | HCAR2MMP1MMP2MMP3MMP9 | |
| SCHEMBL2173042 | 0.85 | CTSK (0.38) | HCAR2MMP1MMP2MMP3MMP9 | |
| SCHEMBL2173055 | 0.85 | CTSK (0.38) | HCAR2MMP1MMP2MMP3MMP9 | |
| SCHEMBL1881287 | 0.83 | HCAR2 (0.39) | HCAR2MMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111479549-B | Aromatic substance mixture containing 8, 8-dimethyl-6, 10-dioxaspiro [4.5] decane | 西姆莱斯有限公司 | 2023-09-12 | — | — | CN | claimed |
| US-11597895-B2 | Aromatic substance mixtures containing 8,8-dimethyl-6,10-dioxaspiro[4,5]decane | SYMRISE AG (DE) | 2023-03-07 | — | — | US | claimed |
| EP-3723709-B1 | PERFUME MIXTURES CONTAINING 8,8-DIMETHYL-6,10-DIOXASPIRO[4,5]DECANE | SYMRISE AG (DE) | 2021-03-31 | — | — | EP | claimed |
| US-20210087500-A1 | AROMATIC SUBSTANCE MIXTURES CONTAINING 8,8-DIMETHYL-6,10-DIOXASPIRO[4,5]DECANE | SYMRISE AG (DE) | 2021-03-25 | — | — | US | claimed |
| CN-111479549-A | Aromatic substance mixture containing 8, 8-dimethyl-6, 10-dioxaspiro [4.5] decane | 西姆莱斯有限公司 | 2020-07-31 | — | — | CN | claimed |
| CN-111479549-B | Aromatic substance mixture containing 8, 8-dimethyl-6, 10-dioxaspiro [4.5] decane | 西姆莱斯有限公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-3723709-B1 | PERFUME MIXTURES CONTAINING 8,8-DIMETHYL-6,10-DIOXASPIRO[4,5]DECANE | SYMRISE AG (DE) | 2021-03-31 | — | — | EP | disclosed |
| CN-111479549-A | Aromatic substance mixture containing 8, 8-dimethyl-6, 10-dioxaspiro [4.5] decane | 西姆莱斯有限公司 | 2020-07-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11597895-B2 | Aromatic substance mixtures containing 8,8-dimethyl-6,10-dioxaspiro[4,5]decane | TAS2R8, TRPM8, DHPS | HCAR2 1193/4885CYP19A1 598/4885MMP1 3837/4885 |
| US-20210087500-A1 | AROMATIC SUBSTANCE MIXTURES CONTAINING 8,8-DIMETHYL-6,10-DIOXASPIRO[4,5]DECANE | TAS2R8, TRPM8, DHPS | HCAR2 1193/4885CYP19A1 598/4885MMP1 3837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.