Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 10/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347791 | 1.00 | HCAR2 (0.52) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL11128184 | 0.88 | HCAR2 (0.47) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL9773642 | 0.85 | HCAR2 (0.57) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL9576299 | 0.85 | HCAR2 (0.57) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL9576188 | 0.85 | HCAR2 (0.47) | HCAR2TSHRACHEBACE1ATM | |
| SCHEMBL6448412 | 0.83 | HCAR2 (0.59) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL11746166 | 0.83 | HCAR2 (0.59) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL6448405 | 0.83 | HCAR2 (0.59) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL9773737 | 0.80 | HCAR2 (0.55) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL11128179 | 0.79 | HCAR2 (0.35) | HCAR2TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142009-A | Crosslinked blend of fumaric acid diesters | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-4868260-A | OXYGEN PERMEABILITY | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1989-09-19 | — | — | US | disclosed |
| EP-0219884-A2 | Hard contact lens material | Tomei Sangyo Kabushiki Kaisha (JP) | 1987-04-29 | — | — | EP | disclosed |